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1

Drug-Like Property Concepts in Pharmaceutical Design

Di, Li, Kerns, Edward, Carter, Guy

Journal:

Current Pharmaceutical Design

Year:

2009

Language:

english

File:

PDF, 369 KB

english, 2009

2

Drug-like Properties: Concepts, Structure Design and Methods || Barriers to Drug Exposure in Living Systems

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

3

Drug-like Properties: Concepts, Structure Design and Methods || Lead-like Compounds

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

4

De Veterum Macarismis; De coronarum apud antiquos vi atque usu; Intermediate Types among Primitive Folk; The House-Door on the Ancient Stage; Inscriptiones Graecae; De l'Aspect verbal en Latin ancien et particulierement dans Terence; De la Phrase a Verbe Etre dans l'Ionien d'Herodote; The Ottoman Empire, 1801-1913; Greek Philosophy. Part I. Thales to Plato;

S., J. L., Dirichlet, G. L., Kochling, J., Carpenter, Edward, Mooney, W. W., Kern, Otto, Barbelenet, D., Miller, William, Burnet, John

Journal:

The Journal of Hellenic Studies

Year:

1914

Language:

english

File:

PDF, 84 KB

english, 1914

5

Automated deep learning design for medical image classification by health-care professionals with no coding experience: a feasibility study

Faes, Livia, Wagner, Siegfried K, Fu, Dun Jack, Liu, Xiaoxuan, Korot, Edward, Ledsam, Joseph R, Back, Trevor, Chopra, Reena, Pontikos, Nikolas, Kern, Christoph, Moraes, Gabriella, Schmid, Martin K, Si

Journal:

The Lancet Digital Health

Year:

2019

Language:

english

File:

PDF, 671 KB

english, 2019

6

[Biotechnology: Pharmaceutical Aspects] Optimizing the “Drug-Like” Properties of Leads in Drug Discovery Volume IV || Solubility, Solubilization and Dissolution in Drug Delivery During Lead Optimization

Borchardt, Ronald T., Kerns, Edward H., Hageman, Michael J., Thakker, Dhiren R., Stevens, James L.

Year:

2006

Language:

english

File:

PDF, 1.27 MB

english, 2006

7

Direct aqueous injection gas chromatography for the analysis of trace organics in water

P.G. Simmonds, Edward Kerns

Journal:

Journal of Chromatography A

Year:

1979

Language:

english

File:

PDF, 732 KB

english, 1979

8

Experimental Determination of the Dynamics of a Mooring System

Kern Jr., Edward C., Milgram, Jerome H., Lincoln, Walter B.

Journal:

Journal of Hydronautics

Year:

1977

Language:

english

File:

PDF, 863 KB

english, 1977

9

Biological assay challenges from compound solubility: strategies for bioassay optimization

Li Di, Edward H. Kerns

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

10

Combined application of parallel artificial membrane permeability assay and Caco-2 permeability assays in drug discovery

Edward H. Kerns, Li Di, Susan Petusky, Michele Farris, Rob Ley, Phil Jupp

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

11

The Critical Role of Passive Permeability in Designing Successful Drugs

Di, Li, Artursson, Per, Avdeef, Alex, Benet, Leslie, Houston, Brian, Kansy, Manfred, Kerns, Edward, LennernÃ¤s, Hans, Smith, Dennis, Sugano, Kiyohiko

Journal:

Year:

2020

File:

PDF, 1.27 MB

2020

12

SPIE Proceedings [SPIE Symposium on Integrated Optoelectronics - San Jose, CA (Thursday 20 January 2000)] Light-Emitting Diodes: Research, Manufacturing, and Applications IV - High-brightness AlGaInN light-emitting diodes

Krames, Michael R., Christenson, G., Collins, Dave, Cook, Lou W., Craford, M. G., Edwards, A., Fletcher, Robert M., Gardner, Nathan F., Goetz, Werner K., Imler, William R., Johnson, Eric, Kern, R. Sco

Year:

2000

Language:

english

File:

PDF, 2.79 MB

english, 2000

13

A transseptal, transsphenoidal approach to the pituitary

Kern, Eugene B., Laws, Edward R., Randall, Raymond V., Westwood, William B.

Journal:

Postgraduate Medicine

Year:

1978

Language:

english

File:

PDF, 1.83 MB

english, 1978

14

High throughput physicochemical profiling for drug discovery

Edward H. Kerns

Journal:

Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 440 KB

english, 2001

15

Drug-like Properties: Concepts, Structure Design and Methods || Solubility

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

16

LC/MS applications in drug development

Mike S. Lee, Edward H. Kerns

Journal:

Mass Spectrometry Reviews

Year:

1999

Language:

english

File:

PDF, 1.27 MB

english, 1999

17

Buspirone metabolite structure profile using a standard liquid chromatographic-mass spectrometric protocol

Edward H. Kerns, Robyn A. Rourick, Kevin J. Volk, Mike S. Lee

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 765 KB

english, 1997

18

Analysis of the clinical utility of a predictive chemosensitivity assay

Edward L. Korn, Vernon K. Sondak, Carl A. Bertelsen, David H. Kern

Journal:

Statistics in Medicine

Year:

1985

Language:

english

File:

PDF, 453 KB

english, 1985

19

Comparing outcomes of anterior cervical discectomy and fusion in workman's versus non–workman's compensation population

Edward J Goldberg, Kern Singh, U Van, Ralph Garretson, Howard S An

Journal:

The Spine Journal

Year:

2002

Language:

english

File:

PDF, 282 KB

english, 2002

20

Monitoring and calibration system for neutrino flux measurement in a high energy dichromatic beam

R. Blair, B. Jin, D. Macfarlane, R.L. Messner, D.B. Novikoff, M.V. Purohit, P.S. Auchincloss, F. Sciulli, M.H. Shaevitz, D. Edwards, H. Edwards, H.E. Fisk, Y. Fukushima, Q.A. Kerns, T. Kondo, P.A. Rap

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

1984

Language:

english

File:

PDF, 1.34 MB

english, 1984

21

Strategies to assess blood–brain barrier penetration

Di, Li, Kerns, Edward H, Carter, Guy T

Journal:

Expert Opinion on Drug Discovery

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

22

Congenital lumbar spinal stenosis: a prospective, control-matched, cohort radiographic analysis

Kern Singh, Dino Samartzis, Alexander R. Vaccaro, Ahmad Nassr, Gunnar B. Andersson, S. Tim Yoon, Frank M. Phillips, Edward J. Goldberg, Howard S. An

Journal:

The Spine Journal

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

23

Factors affecting reoperations after anterior cervical discectomy and fusion within and outside of a Federal Drug Administration investigational device exemption cervical disc replacement trial

Kern Singh, Frank M. Phillips, Dan K. Park, Miguel A. Pelton, Howard S. An, Edward J. Goldberg

Journal:

The Spine Journal

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

24

Investigation of the mechanics of rail seat deterioration and methods to improve the abrasion resistance of concrete sleeper rail seats

Kernes, R. G., Shurpali, A. A., Edwards, J. R., Dersch, M. S., Lange, D. A., Barkan, C. P. L.

Journal:

Proceedings of the Institution of Mechanical Engineers Part F Journal of Rail and Rapid Transit

Year:

2014

Language:

english

File:

PDF, 682 KB

english, 2014

25

Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC–MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC–MS

Li Di, Edward H. Kerns, Susan Q. Li, Guy T. Carter

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

26

Rapid titration of carvedilol in patients with congestive heart failure: A randomized trial of automated telemedicine versus frequent outpatient clinic visits

Jeffrey Spaeder, Samer S. Najjar, Gary Gerstenblith, Gail Hefter, Linda Kern, James G. Palmer, Sheldon H. Gottlieb, Edward K. Kasper

Journal:

American Heart Journal

Year:

2006

Language:

english

File:

PDF, 241 KB

english, 2006

27

65. Factors Affecting Reoperations after ACDF Within and Outside of an FDA IDE Cervical TDR Trial

Kern Singh, Frank Phillips, Daniel Park, Howard An, Edward Goldberg

Journal:

The Spine Journal

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

28

Efficient and Scalable Synthesis of 3,5,7-Trisubstituted 1 H -Indazoles as Potent IKK2 Inhibitors

Lin, Xichen, Busch-Petersen, Jakob, Deng, Jianghe, Edwards, Christine, Zhang, Zhaoguo, Kerns, Jeffrey

Journal:

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

29

The Patient-Centered Medical Home, Electronic Health Records, and Quality of Care

Kern, Lisa M., Edwards, Alison, Kaushal, Rainu

Journal:

Annals of Internal Medicine

Year:

2014

Language:

english

File:

PDF, 166 KB

english, 2014

30

ChemInform Abstract: Stability Challenges in Drug Discovery.

Li Di, Edward H. Kerns

Journal:

Year:

2010

File:

PDF, 15 KB

2010

31

Synthesis and Structure–Activity Relationship Studies of N -Benzyl-2-phenylpyrimidin-4-amine Derivatives as Potent USP1/UAF1 Deubiquitinase Inhibitors with Anticancer Activity against Nonsmall Cell Lung Cancer

Dexheimer, Thomas S., Rosenthal, Andrew S., Luci, Diane K., Liang, Qin, Villamil, Mark A., Chen, Junjun, Sun, Hongmao, Kerns, Edward H., Simeonov, Anton, Jadhav, Ajit, Zhuang, Zhihao, Maloney, David J

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.67 MB

english, 2014

32

Ultra-performance liquid chromatography/tandem mass spectrometric quantification of structurally diverse drug mixtures using an ESI-APCI multimode ionization source

Kate Yu, Li Di, Edward Kerns, Susan Q. Li, Peter Alden, Robert S. Plumb

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 558 KB

english, 2007

33

Patterns of Bat Fatalities at Wind Energy Facilities in North America

EDWARD B. ARNETT, W. KENT BROWN, WALLACE P. ERICKSON, JENNY K. FIEDLER, BRENDA L. HAMILTON, TRAVIS H. HENRY, AAFTAB JAIN, GREGORY D. JOHNSON, JESSICA KERNS, ROLF R. KOFORD, CHARLES P. NICHOLSON, TIMOT

Journal:

Journal of Wildlife Management

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

34

*Poster 166: Improvement in Proprioceptive Function Following Upper-Limb Sensorimotor Training

Jeanne Lanan, Kathy Kern, Edward Hurvitz, Susan Brown

Journal:

Archives of Physical Medicine and Rehabilitation

Year:

2010

Language:

english

File:

PDF, 106 KB

english, 2010

35

Cloud Effects on Distributed Photovoltaic Generation: Slow Transients at the Gardner, Massachusetts Photovoltaic Experiment

Kern, Edward C., Gulachenski, Edward M., Kern, Gregory A.

Journal:

IEEE Power Engineering Review

Year:

1989

Language:

english

File:

PDF, 482 KB

english, 1989

36

Wearable Cardioverter-Defibrillator Use in Patients Perceived to Be at High Risk Early Post-Myocardial Infarction

Epstein, Andrew E., Abraham, William T., Bianco, Nicole R., Kern, Karl B., Mirro, Michael, Rao, Sunil V., Rhee, Edward K., Solomon, Scott D., Szymkiewicz, Steven J.

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 438 KB

english, 2013

37

Blood-Brain Barrier in Drug Discovery (Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs) || Human-Based In Vitro Brain Endothelial Cell Models

Di, Li, Kerns, Edward H.

Year:

2015

Language:

english

File:

PDF, 320 KB

english, 2015

38

Manometric responses to balloon distention in patients with nonobstructive dysphagia

Deschner, William Kern, Maher, Kathleen A., Cattau, Edward L., Benjamin, Stanley B.

Journal:

Gastroenterology

Year:

1989

Language:

english

File:

PDF, 644 KB

english, 1989

39

Cystathionine .GAMMA.-lyase activity in the cephamycin C producer Streptomyces lactamdurans.

KERN, BRIAN A., INAMINE, EDWARD

Journal:

The Journal of Antibiotics

Year:

1981

Language:

english

File:

PDF, 3.40 MB

english, 1981

40

Methodological challenges in indirect treatment comparisons

Singh, Arun, Gopal, Srihari, Kim, Edward, Mathews, Maju, Kern-Sliwa, Jennifer, Turkoz, Ibrahim, Wooller, Annette, Berlin, Jesse

Journal:

International Clinical Psychopharmacology

Year:

2018

Language:

english

File:

PDF, 99 KB

english, 2018

41

Maintenance dose conversion between oral risperidone and paliperidone palmitate 1 month: Practical guidance based on pharmacokinetic simulations

Russu, Alberto, Kern Sliwa, Jennifer, Ravenstijn, Paulien, Singh, Arun, Mathews, Maju, Kim, Edward, Gopal, Srihari

Journal:

International Journal of Clinical Practice

Year:

2018

Language:

english

File:

PDF, 763 KB

english, 2018

42

Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure

Yau, Terrence M., Pagani, Francis D., Mancini, Donna M., Chang, Helena L., Lala, Anuradha, Woo, Y. Joseph, Acker, Michael A., Selzman, Craig H., Soltesz, Edward G., Kern, John A., Maltais, Simon, Char

Journal:

Year:

2019

Language:

english

File:

PDF, 486 KB

english, 2019

43

Characterization of the dogAgoutigene and anonagoutimutation in German Shepherd Dogs

Julie A. Kerns, J. Newton, Tom G. Berryere, Edward M. Rubin, Jan-Fang Cheng, Sheila M. Schmutz, Gregory S. Barsh

Journal:

Mammalian Genome

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

44

Thallium scintigraphic evidence of reversible myocardial ischemia caused by anomalous origin of the left main coronary artery from the anterior sinus of Valsalva

Edward J. Lesnefsky, Jose Pacheco, Kim Adcock, J.Kern Buckner, Karyl M. Van Benthuysen

Journal:

American Heart Journal

Year:

1987

Language:

english

File:

PDF, 2.06 MB

english, 1987

45

Discovery of (2 S ,4 R )-1-(2-Aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic Acid Hydrochloride (GAP-134) 13 , an Orally Active Small Molecule Gap-Junction Modifier for the Treatment of Atrial Fibrillation

Butera, John A., Larsen, Bjarne Due, Hennan, James K., Kerns, Edward, Di, Li, Alimardanov, Asaf, Swillo, Robert E., Morgan, Gwen A., Liu, Kun, Wang, Qiang, Rossman, Eric I., Unwalla, Rayomand, McDonal

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1018 KB

english, 2009

46

Integrity Profiling of High Throughput Screening Hits Using LC-MS and Related Techniques

Edward H. Kerns, Bentham Science Publisher, Li Di, Bentham Science Publisher, Jim Bourassa, Bentham Science Publisher, Jonathan Gross, Bentham Science Publisher, Nelson Huang, Bentham Science Publishe

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

47

In Vitro Solubility Assays in Drug Discovery

Kerns, Edward, Di, Li, Carter, Guy

Journal:

Current Drug Metabolism

Year:

2008

Language:

english

File:

PDF, 156 KB

english, 2008

48

Recent Developments in Practice and Procedure under the Economic Stabilization Program

Mendes Hershman, Willard Z. Carr, Jr., William N. Walker, James C. Paras, George C. Kern, Jr., H. Edward Dunkelberger, Jr., Laurence Silberman, Elliot Bredhoff, Jeffrey S. Berlin, David Wilson and Her

Journal:

The Business Lawyer

Year:

1974

Language:

english

File:

PDF, 4.28 MB

english, 1974

49

Blood-Brain Barrier in Drug Discovery (Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs) || Free Drug Hypothesis for CNS Drug Candidates

Di, Li, Kerns, Edward H.

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

50

Comparison of blood–brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB

Li Di, Edward H. Kerns, Ian F. Bezar, Susan L. Petusky, Youping Huang

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

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